Cullen

The Consultation Letters of Dr William Cullen (1710-1790) at the Royal College of Physicians of Edinburgh

 

[ID:991] From: Dr William Cullen (Professor Cullen) / To: Dr John Gilchrist (of Speddoch) / Regarding: Mr George Mackenzie (McKenzie) (Patient) / 21 June 1780 / (Outgoing)

Reply 'Dr Gilchrist & the use of Cicuta for Mr Mackenzie'

Facsimile

There are 2 images for this document.

[Page 1]


 

[Page 2]


 
 

Metadata

FieldData
DOC ID 991
RCPE Catalogue Number CUL/1/1/13/46
Main Language English
Document Direction Outgoing
Date21 June 1780
Annotation None
TypeScribal copy ( includes Casebook Entry)
Enclosure(s) No enclosure(s)
Autopsy No
Recipe No
Regimen No
Letter of Introduction No
Case Note No
Summary Reply 'Dr Gilchrist & the use of Cicuta for Mr Mackenzie'
Manuscript Incomplete? No
Evidence of Commercial Posting No

Case

Cases that this document belongs to:

Case ID Description Num Docs
[Case ID:1279]
Case of Mr George Mackenzie staying near Dumfries, who has a cough and spits blood. He travels abroad where he dies.
12


People linked to this document

Person IDRole in documentPerson
[PERS ID:1]AuthorDr William Cullen (Professor Cullen)
[PERS ID:115]AddresseeDr John Gilchrist (of Speddoch)
[PERS ID:790]PatientMr George Mackenzie (McKenzie)
[PERS ID:1]Patient's Physician / Surgeon / ApothecaryDr William Cullen (Professor Cullen)
[PERS ID:115]Patient's Physician / Surgeon / ApothecaryDr John Gilchrist (of Speddoch)

Places linked to this document

Role in document Specific Place Settlements / Areas Region Country Global Region Confidence
Place of Writing Cullen's House / Mint Close Edinburgh Edinburgh and East Scotland Europe certain
Destination of Letter Dumfries Borders Scotland Europe inferred

Normalized Text

[Page 1]
Dr Gilchrist q the use of Cicuta for Mr Mackenzie


When I used the Extract some years ago I commonly found
it so ill prepared as not to be depended on; for this reason I
have for some years past employed the powder only. This also
is a little uncertain; the plant is not always chosen at the best
time & properly dried. At present the plant is not in good ↑the best↑
condition.


As to its dose it has been common to begin with a very small
dose & to give it several times a day but this is wrong; for by
thus bringing it on by slow degrees habit counteracts its effects.
You have judged better in giving a larger dose and in
advancing faster but you cannot go any faster tho I
think there is less danger in the use of it than you apprehend.
Even when it had sensible effects I have known it used
very long without any consequence. As to the length



[Page 2]

I would go, I should be ruled by its effects.


Whenever it produces sickness, nausea stricture across
the breast, tremor or giddiness, I go no further then with the dose
till these effects wear off and then I increase the dose a little
again till the like effects are again produced.


Observe that when the dose is pretty quickly brought to
20 grains or half-a-drach if such dose has no sensible effect I conclude
the medicine to be in bad condition & therefore try a
fresh parcel begining however again with a low dose
& increase it as before, but perhaps a little more quickly.

W.C.
Edinburgh 21. June 1780 ----

Diplomatic Text

[Page 1]
Dr Gilchrist q the use of Cicuta for Mr Mackenzie


When I used the Extract some years ago I commonly found
it so ill prepared as not to be depended on; for this reason I
have for some years past employed the powder only. This also
is a little uncertain; the plant is not always chosen at the best
time & properly dried. At present the plant is not in good ↑the best↑
condition.


As to its dose it has been common to begin with a very small
dose & to give it several times a day but this is wrong; for by
thus bringing it on by slow degrees habit counteracts its effects.
You have judged better in giving a larger dose and in
advancing faster but you cannot go any faster tho I
think there is less danger in the use of it than you apprehend.
Even when it had sensible effects I have known it used
very long without any consequence. As to the length



[Page 2]

I would go, I should be ruled by its effects.


Whenever it produces sickness, nausea stricture across
the breast, tremor or giddiness, I go no further then with the dose
till these effects wear off and then I increase the dose a little
again till the like effects are again produced.


Observe that when the dose is pretty quickly brought to
20 gr. or ʒfs if such dose has no sensible effect I conclude
the medicine to be in bad condition & therefore try a
fresh parcel begining however again with a low dose
& increase it as before, but perhaps a little more quickly.

W.C.
Edinr. 21. June 1780 ----

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