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On my arrival here your Patient begun with
the medicine prescribed, and for the first two or three
days imagined herself releived, by her appetite's being
not so craving and a pleasant feeling at the stomach:
in taking the other doses she felt no sensible altera¬
tion only by being more costive than usual, from
which she always found herself stronger and in
better spirits. The next parcel I doubled the quanti¬
ty of Limat: Mart: gr x but on taking them twice
a day, she imagin'd, they occasion'd a want or
rather inability of breathing, therefore I restricted
her to one in the day which did as usual. About
taking the last of the doses of this parcel, she found
the Costiveness rather greater, it being four days
from her having a stool, and never before exceeded
three, she felt that kind of uneasiness which all¬
ways preceeded the looseness, therefore I advis'd, as
she never can bear any purgative or even laxative
medicine to try a suppository which had the effect

not only of procuring a stool but of bringing two
Worms Ascarides alongst with a large slime. I have
made her a third parcell which she now takes in the
same manner as the last and with the same effects.
Upon the whole she seems better. the sick fitts she
formerly complain'd of being neither so frequent
nor violent. She now passes with every stool consi¬
derable quantities of slime which with the
Worms coming away & the Craving appetite, makes
me think she may have them in large quantities.
Pray do you think so? Or if so wou'd any other
medicine be proper? -- The Farinaecous Vegetables
you recommended, she finds agree very well, and
sometimes now ventures upon a little Gruel, Soup & c.
I am with great respect

Dr Cullen
Edinburgh