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Anthony Chamier Esqr. vid. 60.71.81.

I had the honour of Writing to you on the
fifth current in answer to yours of the 27th. last from Matlock
and was very happy in thinking that you was in a train of
recovery, but have been a good deal concerned upon receiving
Mr. Harrison's letter from Derby. However I consider your
distress at Derby as entirely accidental from a fit of Costiveness
which I hope is now entirely over, and that matters will
get again into their former train. What had occasioned that
Costiveness I am not enabled to judge whether it might be

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owing to the frequent use of Opiates with the neglect of your
Laxative, or if without either of these circumstances it could be
imputed to the Steel Powders, you must yourself judge; and
hereafter take your measures accordingly. I am not disposed
to believe the later Cause, as it neither had such effects before
and as Dr. Darwin still allows it to be Continued, tho it
looks somewhat like it, as he advises you taking some
Magnesia and Rhubarb along with the Steel. I have no
objection to the Rhubarb he advises, but I would prefer
the pills I gave you a prescription for, and I can by no means
approve of the Magnesia, as I know that all kinds of
Absorbents defeat the purpose of the rust of Steel. I hope
this will find you at London entirely relieved from what
you suffered at Derby and therefore I have no addition to
make to my letter of the 5th. Current I hope that your Bathing
at Matlock continued to agree with you so much as to
confine your resolution of going as soon as you can to
Brighthelmstone. If you have tried Dr. Darwins prescription
of Columbo root &c. and find it agree with you, I have no
objection to it, but must bid you be aware of its heating
too much. With respect to any other part of his advice
I have no objection or remark to make. I stick entirely
to my former plan and I do not perceive that he differs
from me. That my plan may be effectual with you is
I assure you the anxious wish of,