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Mr. Dunlop

I have the honour of yours of the 25th. but
being in the Country I could not answer it sooner.

I am very much concerned for Mr. Dunlops dis¬
stress and the more so that I find his Case difficult
to manage as the medicines which relieve one dis¬
stress are ready to bring on another as severe. I
thought the Injections proposed by Dr. Campbell
and employed in the manner I advised, the most
effectual, ↑for removing↑ the pressure or as we call it Tenesmus Mr.
Dunlop had been so much troubled with but I find
that perhaps from too frequent use they have
brought on a costiveness equally distressing and in
that case there is nothing but extreme pain would
make me allow of a frequent repetition of the inje¬
ctions. I am very much of your opinion that what
would be of most service to Mr. Dunlop would be

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a laxative that would prevent Costiveness without bringing
on a purging. This is often difficult but I would make
a trial of it. The medicine I have to propose could not
be very safely sent by Post but I here inclose the
prescription for it and you can certainly get it in
very good condition from Air. ↑or rather from Glasgow↑ It consists of two
different liquors that are apt to separate from one
another and therefore when you are to use it you
must take care that the Phial be long and well
shapen so as the two liquors are very exactly and
thoroughly mixed together before you pour out the
dose. This is always to be taken in the morning
and at first it may be a table spoonful but after¬
wards it may be more or less as you find it answers
It should do no more than give one easy motion and
if it does more or less the dose may be diminished
or increased and when you find the proper quantity
it will be enough to give it every second or third

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day. This medicine has commonly this conveniency
that though in most persons it operates moderately
and without griping yet though a person at first
may require a pretty large dose, it commonly happens
that after being repeated several times the dose may
be by degrees diminished so that a small quantity
will commonly answer to keep the belly regular
without purging and if it can be brought to An¬
swer in this way with Mr. Dunlop
it will be the luckiest medicine he can
meet with.

If it should unluckily happen that he has any
return of purging with much Tenesmus I know no
effectual remedy but the injections before proposed but
you are right in thinking that they should be repeated
as seldom as possible and the interposition of the Oil
I have now prescribed will be the most effectual mean
of obviating the Costiveness the injections might produce.
Wishing you heartily relief I am most respectfully
Mr. Dunlop's and Madam your most Obedient
humble Servant

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For Mr. Dunlop of Dunlop