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Mr Glasford

On Thursday last I wrote an answer
to your letter which I had received that day but
by an accident in my family it was not sent to the
Post Office but I hope it came to your hand on
Saturday and see how unlucky our correspondence
is when yours came here on that day I was in
the Country so that I could not answer it till now.

I am much afraid our worthy Patient is decli¬
ning very fast and it is very possible there is a
greater fault in the Epigastric region than you have
yet determined but I am not anxious about the dis¬
covery for if it is as we fear I don't know any
thing that can mend it and we must still treat
the matter upon a footing that admitts of a remedy
that is, a weakness in general and of the stomach
in particular I would by no means insist on the
bitter tincture but if you please to make an

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effort with the Columbo in substance, in water or in
spirits as you please. I have given you my opinion
for it. In the mean time lay aside your acid and
after a weeks trial of the Columbo you may try a
solution of Alkali either mild or Caustic and rather
the former as it will not require broth and it
very possibly may be of service both in correcting
acidity and dissolving slime. I forgot in my last
that I think the Powdered Steel might now
be very properly tried and it can hardly be dis¬
agreeable to his taste or difficult to take. You may
begin with what dose you please but it should be
soon increased to a Scruple or perhaps more twice
a day. After all I think the most probable remedy
would be a long Journey and the Destination to Bath
as proper as any and in the mean time I expect
nothing from the Semicupium but in this and in every
thing else I never meant to dictate to you. I had in

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some measure forgot or at least neglected my debt
to Mr. Barclay but I will do so no longer. I am
as always