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Nothing particular occuring in Coll. Macdonalds
situation is the reason why I have not sooner acknowledged
the receipt of your favour. I wish I could inform
you that He is better, but after the utmost attention
to him, I dare not say that there is any favourable
alteration upon his complaint. The flux continues
much about as frequent as it was; eight or nine
times in the twenty four hours; The only change
I observe is, that for several nights past when
going to bed, a greater quantity of Pus like matter
has been voided with his stools, and with less pain,
and for these two last nights, the discharge was pure
matter without any ex crementitious mixture

This last discharge makes me sometimes flatter
myself, that a kindly suppuration may take place,
therefore I take the first opportunity of informing

His stomach has been so delicate, he could not use
the strengthening mixture prescribed last by you. But
to assist his appetite and to strengthen him, he takes
daily, a glass of Port wine and Bark, An Ounce of
Bark to a bottle of wine. He drinks the spaw water
regularly, and still thinks his strength and spirits are
both better which in spite of the Flux they certainly
are. Riding on Horseback disagreed with him;
By resting now upon a couch, he finds himself considerably
easier and his stools fewer.

He is a little more attentive to Regimen, confines
himself now to three glasses of wine at diner. With
the Colonel's best compliments, and expecting your
answer as soon as convenient,

To
Dr. Cullen
Edinr.