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I was duly favoured with yours of the
20th. Ulto., but being from home ever since untill
a few days ago, have not had an oppty. of
writing you an answer before I had it my
power to apply any of the remedies prescribed
for Mrs. McKie, such symptoms has appear'd
as leads me to believe she is with Child
& in this case it may neither be proper or
safe to apply them, she has now been
obstructed for these two last times of her
menses, & besides has every other symptom that
generally attends pregnancy, attended with
a most obstinate Costiveness, so that degree
that she is often a whole week without
have any passage. The other discharge tho
not altogether gone is considerably lessened -

Will you be so good as advise how to act -
I would not say a word respecting myself.
Altho I am upon the whole pretty well
yet I have within these few weeks been much
troubled with frequent returns of the bleeding
at the Anus with being able to account
for the cause, & sometimes to such a degree
as to alarm me, it is attended with no pain
in the parts, at these times I find any Bowells
much disordered & a kind of weakness in the
whole frame, the only way I can get the bleeding
stoped is by lying in on one side & pushing
up the protruded part of the Anus, - say is
there any thing that can be done to strengthen
the parts -- I am sorry I was not in way when
Mr. Naismith left this place, but shall by
the first safe hand remit You for your advice
in mean time shall be glad to hear from you

Doctor William Cullen
Edinburgh