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Mrs Sinclair, a married Lady, at 29 years of age,
had always a delicate appearance, & complaind
frequently of Headaches, more seldom of sickness
of stomach & pains of the side, but never labour¬
ed under any remarkable Disease till lately
She has suckled three children, of which the
youngest was weaned in June last. The nursing
always seemed to agree well with Her. ––––

Her Menses have been regular till the last
period, when they did not appear as usual. ––

From a prejudice at medicines, she
concealed the present complaint for some time,
& thereby I am rendered unable to describe the
beginning or progress of them with any certainty
previous to my first seeing Mrs Sinclair, which
was a fortnight ago, at the earnest desire of her
Friends, & contrary to her own inclination ––

I was then informed that she ↑had↑ been losing
her flesh & colour gradually for some months. That
she had a slight Cough, & a degree of Looseness for some

After attending Her a few Days I observe the follow¬
ing appearances.

Thro' the Day, but much more in the night time,
She coughs up a good deal of clear Phlegm, & along with
it, but distinct from it, at each time a small
quantity of thick yellowish matter.

After coughing, or even moderate motion of the
body, her Breathing is sensibly affected, & becomes
very uneasy, & sometimes there is a slight pain
in the left side of the thorax, but this last less
now than formerly.

In the morning & forenoon, the Heat of her body
is of a natural temperature, & the Pulse not above
70 or 75. –– About mid-day a sense of Cold comes
on, & I have twice seen it arise to a consider¬
able tremor: thro' the afternoon She is very
warm, & her Pulse very quick, tho' always weak,
but returning to its natural motion thro' the
night. About the morning there is commonly a
sweat over her body. ––––

She has scarce any appetite, but there is a
considerable degree of thirst; & her Tonge is

Her whole Body is quite emaciated, & her counte¬
nance hollow & pale, except while the hot
fit prevails in the afternoon and her
strength is low, that she cannot walk the
stairs, & scarcely thro' the room, without support.

Her Diet consists of milk, bread, & Rice, the
broth of a Fowl, & at Breakfast an Egg. Ass milk
was tried & discontinued as it seemed to increase the
purging. ––––

Some time ago she took a vomit at the desire
of an acquaintance, & threw up with it a good
deal of Bilious coloured matter. –– As she thought
it occasioned some pain in her side, & found it
weakening, this was not repeated.

She has got one Dose of Rhubarb, which operated.
& there was no return of the Diarrhea for two Days
after it.

It is proposed to continue the above regimen, to
moderate the Diarrhea by small Doses of Opiates,